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siRNA Targeting the 2A(pro) Genomic Region Prevents Enterovirus 71 Replication In Vitro

Enterovirus 71 (EV71) is the most important etiological agent of hand, foot, and mouth disease (HFMD) in young children, which is associated with severe neurological complications and has caused significant mortalities in recent HFMD outbreaks in Asia. However, there is no effective antiviral therap...

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Detalles Bibliográficos
Autores principales: Liu, Haibing, Qin, Yanyan, Kong, Zhenzhen, Shao, Qixiang, Su, Zhaoliang, Wang, Shengjun, Chen, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757562/
https://www.ncbi.nlm.nih.gov/pubmed/26886455
http://dx.doi.org/10.1371/journal.pone.0149470