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Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease
Alzheimer’s disease (AD) is characterised by a progressive loss of cognitive functions. Histopathologically, AD is defined by the presence of extracellular amyloid plaques containing Aβ and intracellular neurofibrillary tangles composed of hyperphosphorylated tau proteins. According to the now well-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757605/ https://www.ncbi.nlm.nih.gov/pubmed/26729186 http://dx.doi.org/10.1007/s40265-015-0529-0 |