Clinical sequencing: is WGS the better WES?

Current clinical next-generation sequencing is done by using gene panels and exome analysis, both of which involve selective capturing of target regions. However, capturing has limitations in sufficiently covering coding exons, especially GC-rich regions. We compared whole exome sequencing (WES) wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Meienberg, Janine, Bruggmann, Rémy, Oexle, Konrad, Matyas, Gabor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757617/
https://www.ncbi.nlm.nih.gov/pubmed/26742503
http://dx.doi.org/10.1007/s00439-015-1631-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757617/
https://www.ncbi.nlm.nih.gov/pubmed/26742503
http://dx.doi.org/10.1007/s00439-015-1631-9

Ejemplares similares