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Mutant p53 and ETS2, a Tale of Reciprocity

TP53 is one of the most frequently inactivated tumor suppressor genes in human cancer. However, unlike other tumor suppressor genes whose expression is lost, TP53 is usually inactivated as a result of a single nucleotide change within the coding region. Typically, these single nucleotide mutations r...

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Detalles Bibliográficos
Autor principal: Martinez, Luis Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757666/
https://www.ncbi.nlm.nih.gov/pubmed/26925389
http://dx.doi.org/10.3389/fonc.2016.00035