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Glycosylated Notch and Cancer

Glycosylation is one of the key components influencing several signaling pathways implicated in cell survival and growth. The Notch signaling pathway plays a pivotal role in numerous cell fate specifications during metazoan development. Both Notch and its ligands are repeatedly glycosylated by the a...

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Detalles Bibliográficos
Autores principales: Pakkiriswami, Shanmugasundaram, Couto, Africa, Nagarajan, Usha, Georgiou, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757683/
https://www.ncbi.nlm.nih.gov/pubmed/26925390
http://dx.doi.org/10.3389/fonc.2016.00037