Cargando…

Glycosylated Notch and Cancer

Glycosylation is one of the key components influencing several signaling pathways implicated in cell survival and growth. The Notch signaling pathway plays a pivotal role in numerous cell fate specifications during metazoan development. Both Notch and its ligands are repeatedly glycosylated by the a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pakkiriswami, Shanmugasundaram, Couto, Africa, Nagarajan, Usha, Georgiou, Marios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757683/ https://www.ncbi.nlm.nih.gov/pubmed/26925390 http://dx.doi.org/10.3389/fonc.2016.00037

Ejemplares similares

Sugar tags and tumorigenesis
por: Nagarajan, Usha, et al.
Publicado: (2015)

An apicobasal gradient of Rac activity determines protrusion form and position
por: Couto, Africa, et al.
Publicado: (2017)

Notching on Cancer’s Door: Notch Signaling in Brain Tumors
por: Teodorczyk, Marcin, et al.
Publicado: (2015)

Significant Roles of Notch O-Glycosylation in Cancer
por: Wang, Weiwei, et al.
Publicado: (2022)

Glycosylation Changes in Prostate Cancer Progression
por: Butler, William, et al.
Publicado: (2021)

Notch signaling, hypoxia, and cancer
por: Guo, Mingzhou, et al.
Publicado: (2023)

The Role of Glycosylation in Breast Cancer Metastasis and Cancer Control
por: Kölbl, Alexandra C., et al.
Publicado: (2015)

Glycosylated Nanoparticles for Cancer-Targeted Drug Delivery
por: Torres-Pérez, Sergio Andrés, et al.
Publicado: (2020)

Abnormal Glycosylation of Cancer Stem Cells and Targeting Strategies
por: Khan, Thahomina, et al.
Publicado: (2021)

Glycosylation in Cervical Cancer: New Insights and Clinical Implications
por: Xu, Zhiwei, et al.
Publicado: (2021)

Non-Canonical Notch Signaling in Cancer and Immunity
por: Ayaz, Furkan, et al.
Publicado: (2014)

Editorial: Glycosylation Changes in Cancer: An Innovative Frontier at the Interface of Cancer and Glycobiology
por: Freire-de-Lima, Leonardo, et al.
Publicado: (2016)

Glycosylation of Glycolipids in Cancer: Basis for Development of Novel Therapeutic Approaches
por: Daniotti, Jose L., et al.
Publicado: (2013)

Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks
por: Peixoto, Andreia, et al.
Publicado: (2019)

The Role of Notch in the Cardiovascular System: Potential Adverse Effects of Investigational Notch Inhibitors
por: Rizzo, Paola, et al.
Publicado: (2015)

Editorial: Cancer Metabolism: Molecular Targeting and Implications for Therapy
por: Ganapathy-Kanniappan, Shanmugasundaram
Publicado: (2017)

Moving Breast Cancer Therapy up a Notch
por: Mollen, Erik W. J., et al.
Publicado: (2018)

Glycosylation in Cancer: Interplay between Multidrug Resistance and Epithelial-to-Mesenchymal Transition?
por: da Fonseca, Leonardo Marques, et al.
Publicado: (2016)

Glycosylated Cathepsin V Serves as a Prognostic Marker in Lung Cancer
por: Yang, Lewei, et al.
Publicado: (2022)

Clinical Significance of NOTCH1 and NOTCH2 Expression in Gastric Carcinomas: An Immunohistochemical Study
por: Bauer, Lukas, et al.
Publicado: (2015)

Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer
por: Baker, Andrew T., et al.
Publicado: (2014)

Notch Signaling in Neuroendocrine Tumors
por: Crabtree, Judy S., et al.
Publicado: (2016)

Altered Tumor-Cell Glycosylation Promotes Metastasis
por: Häuselmann, Irina, et al.
Publicado: (2014)

Serum Protein N-Glycosylation Signatures of Neuroblastoma
por: Qin, Wenjun, et al.
Publicado: (2021)

Sweet and Sour: The Impact of Differential Glycosylation in Cancer Cells Undergoing Epithelial–Mesenchymal Transition
por: Freire-de-Lima, Leonardo
Publicado: (2014)

Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer
por: Vasconcelos-dos-Santos, Andréia, et al.
Publicado: (2015)

CD44 Glycosylation as a Therapeutic Target in Oncology
por: Liao, Chengcheng, et al.
Publicado: (2022)

NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status
por: Baldoni, Stefano, et al.
Publicado: (2021)

NOTCH3 is a Prognostic Factor and Is Correlated With Immune Tolerance in Gastric Cancer
por: Cui, Yuehong, et al.
Publicado: (2021)

Hypoxia Alters Epigenetic and N-Glycosylation Profiles of Ovarian and Breast Cancer Cell Lines in-vitro
por: Greville, Gordon, et al.
Publicado: (2020)

A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion
por: Canales Coutiño, Brenda, et al.
Publicado: (2020)

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
por: Rosati, Emanuela, et al.
Publicado: (2018)

Editorial: The notch signaling pathway in lymphoid malignancies
por: Fais, Franco, et al.
Publicado: (2023)

Genetically Modeled Mice with Mutations in Mitochondrial Metabolic Enzymes for the Study of Cancer
por: Piruat, José I., et al.
Publicado: (2014)

Congenital diseases caused by defective O-glycosylation of Notch receptors
por: Tashima, Yuko, et al.
Publicado: (2018)

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
por: Sosa Iglesias, Venus, et al.
Publicado: (2018)

Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila
por: Pandey, Ashutosh, et al.
Publicado: (2019)

Taming Tumor Glycolysis and Potential Implications for Immunotherapy
por: Ganapathy-Kanniappan, Shanmugasundaram
Publicado: (2017)

Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells
por: de Queiroz, Rafaela Muniz, et al.
Publicado: (2019)

Detection of Glycosylated Markers From Cancer Stem Cells With ColoSTEM Dx Kit for Earlier Prediction of Colon Cancer Aggressiveness
por: Blondy, Sabrina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c2dqgjl2l7m470rnivbr3pbv7l