Synergistic Effects of Simvastatin and Irinotecan against Colon Cancer Cells with or without Irinotecan Resistance

Aims. We here investigated whether the combination of simvastatin and irinotecan could induce the synergistic effect on colon cancer cells with or without resistance to irinotecan. Methods. We investigated cell proliferation assay and assessed cell death detection ELISA and caspase-3 activity assay...

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Detalles Bibliográficos
Autores principales: Jang, Hyun Joo, Hong, Eun Mi, Jang, Juah, Choi, Jung Eun, Park, Se Woo, Byun, Hyun Woo, Koh, Dong Hee, Choi, Min Ho, Kae, Sea Hyub, Lee, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757714/
https://www.ncbi.nlm.nih.gov/pubmed/26966430
http://dx.doi.org/10.1155/2016/7891374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757714/
https://www.ncbi.nlm.nih.gov/pubmed/26966430
http://dx.doi.org/10.1155/2016/7891374

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