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Generation of KCL016 research grade human embryonic stem cell line carrying a mutation in VHL gene
The KCL016 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting splicing site of the VHL gene encoding von Hippel–Lindau tumor suppressor E3 ubiquitin protein ligase (676 + 3A > T). The ICM was isolated using laser mi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757726/ https://www.ncbi.nlm.nih.gov/pubmed/27345783 http://dx.doi.org/10.1016/j.scr.2015.12.003 |