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Generation of KCL016 research grade human embryonic stem cell line carrying a mutation in VHL gene

The KCL016 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting splicing site of the VHL gene encoding von Hippel–Lindau tumor suppressor E3 ubiquitin protein ligase (676 + 3A > T). The ICM was isolated using laser mi...

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Detalles Bibliográficos
Autores principales: Miere, Cristian, Hewitson, Heema, Wood, Victoria, Kadeva, Neli, Cornwell, Glenda, Codognotto, Stefano, Stephenson, Emma, Ilic, Dusko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757726/
https://www.ncbi.nlm.nih.gov/pubmed/27345783
http://dx.doi.org/10.1016/j.scr.2015.12.003