Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA

The selective targeting of mismatched DNA overexpressed in cancer cells is an appealing strategy in designing cancer diagnosis and therapy protocols. Few luminescent probes that specifically detect intracellular mismatched DNA have been reported. Here we used Pt(II) complexes with luminescence sensi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fung, Sin Ki, Zou, Taotao, Cao, Bei, Chen, Tianfeng, To, Wai-Pong, Yang, Chen, Lok, Chun-Nam, Che, Chi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757794/
https://www.ncbi.nlm.nih.gov/pubmed/26883164
http://dx.doi.org/10.1038/ncomms10655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757794/
https://www.ncbi.nlm.nih.gov/pubmed/26883164
http://dx.doi.org/10.1038/ncomms10655

Ejemplares similares