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New England harbor seal H3N8 influenza virus retains avian-like receptor specificity

An influenza H3N8 virus, carrying mammalian adaptation mutations, was isolated from New England harbor seals in 2011. We sought to assess the risk of its human transmissibility using two complementary approaches. First, we tested the binding of recombinant hemagglutinin (HA) proteins of seal H3N8 an...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Hussein, Islam T. M., Krammer, Florian, Ma, Eric, Estrin, Michael, Viswanathan, Karthik, Stebbins, Nathan W., Quinlan, Devin S., Sasisekharan, Ram, Runstadler, Jonathan
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757820/
https://www.ncbi.nlm.nih.gov/pubmed/26888262
http://dx.doi.org/10.1038/srep21428