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Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases
The RecQ4 helicase belongs to the ubiquitous RecQ family but its exact role in the cell is not completely understood. In addition to the helicase domain, RecQ4 has a unique N-terminal part that is essential for viability and is constituted by a region homologous to the yeast Sld2 replication initiat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757822/ https://www.ncbi.nlm.nih.gov/pubmed/26888063 http://dx.doi.org/10.1038/srep21501 |