Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

The RecQ4 helicase belongs to the ubiquitous RecQ family but its exact role in the cell is not completely understood. In addition to the helicase domain, RecQ4 has a unique N-terminal part that is essential for viability and is constituted by a region homologous to the yeast Sld2 replication initiat...

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Detalles Bibliográficos
Autores principales: Marino, Francesca, Mojumdar, Aditya, Zucchelli, Chiara, Bhardwaj, Amit, Buratti, Emanuele, Vindigni, Alessandro, Musco, Giovanna, Onesti, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757822/
https://www.ncbi.nlm.nih.gov/pubmed/26888063
http://dx.doi.org/10.1038/srep21501

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