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Determination of thiol metabolites in human urine by stable isotope labeling in combination with pseudo-targeted mass spectrometry analysis

Precursor ion scan and multiple reaction monitoring scan (MRM) are two typical scan modes in mass spectrometry analysis. Here, we developed a strategy by combining stable isotope labeling (IL) with liquid chromatography-mass spectrometry (LC-MS) under double precursor ion scan (DPI) and MRM for anal...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Qi, Chu-Bo, Zhu, Quan-Fei, Yuan, Bi-Feng, Feng, Yu-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757830/
https://www.ncbi.nlm.nih.gov/pubmed/26888486
http://dx.doi.org/10.1038/srep21433