Amelioration of intracellular stress and reduction of neural tube defects in embryos of diabetic mice by phytochemical quercetin

Diabetes mellitus in early pregnancy causes birth defects, including neural tube defects (NTDs). Hyperglycemia increases production of nitric oxide (NO) through NO synthase 2 (Nos2) and reactive oxygen species (ROS), generating nitrosative and oxidative stress conditions in the embryo. The present s...

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Detalles Bibliográficos
Autores principales: Cao, Lixue, Tan, Chengyu, Meng, Fantong, Liu, Peiyan, Reece, E. Albert, Zhao, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757833/
https://www.ncbi.nlm.nih.gov/pubmed/26887929
http://dx.doi.org/10.1038/srep21491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757833/
https://www.ncbi.nlm.nih.gov/pubmed/26887929
http://dx.doi.org/10.1038/srep21491

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