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A tRNA methyltransferase paralog is important for ribosome stability and cell division in Trypanosoma brucei

Most eukaryotic ribosomes contain 26/28S, 5S, and 5.8S large subunit ribosomal RNAs (LSU rRNAs) in addition to the 18S rRNA of the small subunit (SSU rRNA). However, in kinetoplastids, a group of organisms that include medically important members of the genus Trypanosoma and Leishmania, the 26/28S l...

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Detalles Bibliográficos
Autores principales: Fleming, Ian M. C., Paris, Zdeněk, Gaston, Kirk W., Balakrishnan, R., Fredrick, Kurt, Rubio, Mary Anne T., Alfonzo, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757839/
https://www.ncbi.nlm.nih.gov/pubmed/26888608
http://dx.doi.org/10.1038/srep21438