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BIRC3 is a novel driver of therapeutic resistance in Glioblastoma

Genome-wide analysis of glioblastoma (GBM) reveals pervasive aberrations in apoptotic signaling pathways that collectively contribute to therapeutic resistance. Inhibitors of apoptosis proteins (IAP) exert critical control on the terminal segment of apoptosis leading to apoptosis evasion. In this st...

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Detalles Bibliográficos
Autores principales: Wang, Dapeng, Berglund, Anders, Kenchappa, Rajappa S., Forsyth, Peter A., Mulé, James J., Etame, Arnold B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757860/
https://www.ncbi.nlm.nih.gov/pubmed/26888114
http://dx.doi.org/10.1038/srep21710