Dysfunction of Wntless triggers the retrograde Golgi-to-ER transport of Wingless and induces ER stress

Secreted Wnts play diverse roles in a non-cell-autonomous fashion. However, the cell-autonomous effect of unsecreted Wnts remains unknown. Endoplasmic reticulum (ER) stress is observed in specialized secretory cells and participates in pathophysiological processes. The correlation between Wnt secret...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Peng, Zhou, Lujun, Pei, Chunli, Lin, Xinhua, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757895/
https://www.ncbi.nlm.nih.gov/pubmed/26887613
http://dx.doi.org/10.1038/srep19418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757895/
https://www.ncbi.nlm.nih.gov/pubmed/26887613
http://dx.doi.org/10.1038/srep19418

Ejemplares similares