CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation

Summary: The CRISPR/Cas9 system was recently developed as a powerful and flexible technology for targeted genome engineering, including genome editing (altering the genetic sequence) and gene regulation (without altering the genetic sequence). These applications require the design of single guide RN...

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Detalles Bibliográficos
Autores principales: Liu, Honglei, Wei, Zheng, Dominguez, Antonia, Li, Yanda, Wang, Xiaowo, Qi, Lei S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757951/
https://www.ncbi.nlm.nih.gov/pubmed/26209430
http://dx.doi.org/10.1093/bioinformatics/btv423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757951/
https://www.ncbi.nlm.nih.gov/pubmed/26209430
http://dx.doi.org/10.1093/bioinformatics/btv423

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