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Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is an aggressive malignant disorder of lymphoid progenitor cells in both children and adults. Although improvements in contemporary therapy and development of new treatment strategies have led to dramatic increases in the cure rate in children with ALL,...

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Detalles Bibliográficos
Autores principales: Shi, Pei-Jie, Xu, Lu-Hong, Lin, Kang-Yu, Weng, Wen-jun, Fang, Jian-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757994/
https://www.ncbi.nlm.nih.gov/pubmed/26892465
http://dx.doi.org/10.1186/s13045-016-0241-x