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Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology

BACKGROUND: The recent outbreak of Ebola has been cited as the largest in history. Despite this global health crisis, few drugs are available to efficiently treat Ebola infections. Drug repurposing provides a potentially efficient solution to accelerating the development of therapeutic approaches in...

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Detalles Bibliográficos
Autores principales: Zhao, Zheng, Martin, Che, Fan, Raymond, Bourne, Philip E., Xie, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757998/
https://www.ncbi.nlm.nih.gov/pubmed/26887654
http://dx.doi.org/10.1186/s12859-016-0941-9