Cargando…

TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18–1/syntaxin1/SNAP-25 mediated fusion

Transient receptor potential (TRP) A1 and V1 channels relay sensory signals, yet little is known about their transport to the plasmalemma during inflammation. Herein, TRPA1 and TRPV1 were found on vesicles containing calcitonin gene-related peptide (CGRP), accumulated at sites of exo- and endo-cytos...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Jianghui, Wang, Jiafu, Steinhoff, Martin, Dolly, James Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758037/
https://www.ncbi.nlm.nih.gov/pubmed/26888187
http://dx.doi.org/10.1038/srep21226