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Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice

Endocrine and exocrine pancreas tissues are both derived from the posterior foregut endoderm, however, the interdependence of these two cell types during their formation is not well understood. In this study, we generated mutant mice, in which the exocrine tissue is hypoplastic, in order to reveal a...

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Detalles Bibliográficos
Autores principales: Kodama, Sota, Nakano, Yasuhiro, Hirata, Koji, Furuyama, Kenichiro, Horiguchi, Masashi, Kuhara, Takeshi, Masui, Toshihiko, Kawaguchi, Michiya, Gannon, Maureen, Wright, Christopher V. E., Uemoto, Shinji, Kawaguchi, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758062/
https://www.ncbi.nlm.nih.gov/pubmed/26887806
http://dx.doi.org/10.1038/srep21211