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Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice
Endocrine and exocrine pancreas tissues are both derived from the posterior foregut endoderm, however, the interdependence of these two cell types during their formation is not well understood. In this study, we generated mutant mice, in which the exocrine tissue is hypoplastic, in order to reveal a...
Autores principales: | Kodama, Sota, Nakano, Yasuhiro, Hirata, Koji, Furuyama, Kenichiro, Horiguchi, Masashi, Kuhara, Takeshi, Masui, Toshihiko, Kawaguchi, Michiya, Gannon, Maureen, Wright, Christopher V. E., Uemoto, Shinji, Kawaguchi, Yoshiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758062/ https://www.ncbi.nlm.nih.gov/pubmed/26887806 http://dx.doi.org/10.1038/srep21211 |
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