Conserved miR-26b enhances ovarian granulosa cell apoptosis through HAS2-HA-CD44-Caspase-3 pathway by targeting HAS2

The hyaluronan synthase 2 (HAS2)-hyaluronic acid (HA)-CD44-Caspase-3 pathway is involved in ovarian granulosa cell (GC) functions in mammals. HAS2 is a key enzyme required for HA synthesis and is the key factor in this pathway. However, the regulation of HAS2 and the HAS2-mediated pathway by microRN...

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Detalles Bibliográficos
Autores principales: Liu, Jiying, Tu, Fei, Yao, Wang, Li, Xinyu, Xie, Zhuang, Liu, Honglin, Li, Qifa, Pan, Zengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758074/
https://www.ncbi.nlm.nih.gov/pubmed/26887530
http://dx.doi.org/10.1038/srep21197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758074/
https://www.ncbi.nlm.nih.gov/pubmed/26887530
http://dx.doi.org/10.1038/srep21197

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