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Aggrecan heterogeneity in articular cartilage from patients with osteoarthritis

BACKGROUND: Aggrecan degradation is the hallmark of cartilage degeneration in osteoarthritis (OA), though it is unclear whether a common proteolytic process occurs in all individuals. METHODS: Aggrecan degradation in articular cartilage from the knees of 33 individuals with OA, who were undergoing j...

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Detalles Bibliográficos
Autores principales: Mort, John S., Geng, Yeqing, Fisher, William D., Roughley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758135/
https://www.ncbi.nlm.nih.gov/pubmed/26891838
http://dx.doi.org/10.1186/s12891-016-0944-8