Microwave gallium-68 radiochemistry for kinetically stable bis(thiosemicarbazone) complexes: structural investigations and cellular uptake under hypoxia

We report the microwave synthesis of several bis(thiosemicarbazones) and the rapid gallium-68 incorporation to give the corresponding metal complexes. These proved kinetically stable under ‘cold’ and ‘hot’ biological assays and were investigated using laser scanning confocal microscopy, flow cytomet...

Descripción completa

Detalles Bibliográficos
Autores principales: Alam, Israt S., Arrowsmith, Rory L., Cortezon-Tamarit, Fernando, Twyman, Frazer, Kociok-Köhn, Gabriele, Botchway, Stanley W., Dilworth, Jonathan R., Carroll, Laurence, Aboagye, Eric O., Pascu, Sofia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758186/
https://www.ncbi.nlm.nih.gov/pubmed/26583314
http://dx.doi.org/10.1039/c5dt02537k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758186/
https://www.ncbi.nlm.nih.gov/pubmed/26583314
http://dx.doi.org/10.1039/c5dt02537k

Ejemplares similares