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Microwave gallium-68 radiochemistry for kinetically stable bis(thiosemicarbazone) complexes: structural investigations and cellular uptake under hypoxia
We report the microwave synthesis of several bis(thiosemicarbazones) and the rapid gallium-68 incorporation to give the corresponding metal complexes. These proved kinetically stable under ‘cold’ and ‘hot’ biological assays and were investigated using laser scanning confocal microscopy, flow cytomet...
Autores principales: | Alam, Israt S., Arrowsmith, Rory L., Cortezon-Tamarit, Fernando, Twyman, Frazer, Kociok-Köhn, Gabriele, Botchway, Stanley W., Dilworth, Jonathan R., Carroll, Laurence, Aboagye, Eric O., Pascu, Sofia I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758186/ https://www.ncbi.nlm.nih.gov/pubmed/26583314 http://dx.doi.org/10.1039/c5dt02537k |
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