NADPH oxidase 3-associated oxidative stress and caspase 3-dependent apoptosis in the cochleae of D-galactose-induced aged rats

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Oxidative damage to mitochondrial DNA (mtDNA) and cell apoptosis are heavily implicated in aging. Our previous study established a mimetic rat model of aging in the cochleae using D-galactose (D-gal), and revealed that chronic injection of D-gal can increase oxidative stress and mtDNA common deletio...

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Detalles Bibliográficos
Autores principales: DU, ZHENGDE, LI, SHUO, LIU, LIN, YANG, QIONG, ZHANG, HONGWEI, GAO, CHUNSHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758280/
https://www.ncbi.nlm.nih.gov/pubmed/26498835
http://dx.doi.org/10.3892/mmr.2015.4430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758280/
https://www.ncbi.nlm.nih.gov/pubmed/26498835
http://dx.doi.org/10.3892/mmr.2015.4430

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