Knockdown of eukaryotic translation initiation factor 4E suppresses cell growth and invasion, and induces apoptosis and cell cycle arrest in a human lung adenocarcinoma cell line

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Eukaryotic translation initiation factor 4E (eIF4E) was shown to be upregulated in malignant human tumors. To assess the effect of downregulation of eIF4E on the proliferation and invasiveness of a human lung adenocarcinoma cell line, a short hairpin (sh)RNA targeting eIF4E was constructed and trans...

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Detalles Bibliográficos
Autores principales: CHEN, BAOFU, ZHANG, BO, XIA, LILONG, ZHANG, JIAN, CHEN, YU, HU, QUANTENG, ZHU, CHENGCHU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758288/
https://www.ncbi.nlm.nih.gov/pubmed/26498338
http://dx.doi.org/10.3892/mmr.2015.4468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758288/
https://www.ncbi.nlm.nih.gov/pubmed/26498338
http://dx.doi.org/10.3892/mmr.2015.4468

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