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Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction
Renal fibrosis is the major cause of chronic kidney disease, and the Rho/Rho-associated coiled-coil kinase (ROCK) signaling cascade is involved in the renal fibrotic processes. Several studies have reported that ROCK inhibitors attenuate renal fibrosis. However, the mechanism of this process remains...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758322/ https://www.ncbi.nlm.nih.gov/pubmed/26498136 http://dx.doi.org/10.3892/mmr.2015.4467 |