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Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction
Renal fibrosis is the major cause of chronic kidney disease, and the Rho/Rho-associated coiled-coil kinase (ROCK) signaling cascade is involved in the renal fibrotic processes. Several studies have reported that ROCK inhibitors attenuate renal fibrosis. However, the mechanism of this process remains...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758322/ https://www.ncbi.nlm.nih.gov/pubmed/26498136 http://dx.doi.org/10.3892/mmr.2015.4467 |