The unfolded protein response and its potential role in Huntington's disease elucidated by a systems biology approach

Huntington ´s disease (HD) is a progressive, neurodegenerative disease with a fatal outcome. Although the disease-causing gene (huntingtin) has been known for over 20 years, the exact mechanisms leading to neuronal cell death are still controversial. One potential mechanism contributing to the massi...

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Detalles Bibliográficos
Autores principales: Kalathur, Ravi Kiran Reddy, Giner-Lamia, Joaquin, Machado, Susana, Barata, Tania, Ayasolla, Kameshwar R S, Futschik, Matthias E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758378/
https://www.ncbi.nlm.nih.gov/pubmed/26949515
http://dx.doi.org/10.12688/f1000research.6358.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758378/
https://www.ncbi.nlm.nih.gov/pubmed/26949515
http://dx.doi.org/10.12688/f1000research.6358.2

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