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Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials
Detecting treatment efficacy using cognitive change in trials of cerebral small vessel disease (SVD) has been challenging, making the use of surrogate markers such as magnetic resonance imaging (MRI) attractive. We determined the sensitivity of MRI to change in SVD and used this information to calcu...
Autores principales: | Benjamin, Philip, Zeestraten, Eva, Lambert, Christian, Chis Ster, Irina, Williams, Owen A, Lawrence, Andrew J, Patel, Bhavini, MacKinnon, Andrew D, Barrick, Thomas R, Markus, Hugh S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758545/ https://www.ncbi.nlm.nih.gov/pubmed/26036939 http://dx.doi.org/10.1038/jcbfm.2015.113 |
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