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Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies

PURPOSE: (S)-4-(3-[(18)F]Fluoropropyl)-L-glutamic acid (18F-FSPG) is a novel radiopharmaceutical for Positron Emission Tomography (PET) imaging. It is a glutamate analogue that can be used to measure x(C)(-) transporter activity. This study was performed to assess the feasibility of 18F-FSPG for ima...

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Detalles Bibliográficos
Autores principales: Mittra, Erik S., Koglin, Norman, Mosci, Camila, Kumar, Meena, Hoehne, Aileen, Keu, Khun Visith, Iagaru, Andrei H., Mueller, Andre, Berndt, Mathias, Bullich, Santiago, Friebe, Matthias, Schmitt-Willich, Heribert, Gekeler, Volker, Fels, Lüder M., Bacher-Stier, Claudia, Moon, Dae Hyuk, Chin, Frederick T., Stephens, Andrew W., Dinkelborg, Ludger M., Gambhir, Sanjiv S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758607/
https://www.ncbi.nlm.nih.gov/pubmed/26890637
http://dx.doi.org/10.1371/journal.pone.0148628