Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells

AIM: To evaluate the anti-inflammatory, anti-oxidant and antifibrotic effects of carvedilol (CARV) in rats with ethanol-induced liver injury. METHODS: Liver injury was induced by gavage administration of alcohol (7 g/kg) for 28 consecutive days. Eighty Wistar rats were pretreated with oral CARV at 1...

Descripción completa

Detalles Bibliográficos
Autores principales: de Araújo Júnior, Raimundo Fernandes, Garcia, Vinícius Barreto, Leitão, Renata Ferreira de Carvalho, Brito, Gerly Anne de Castro, Miguel, Emilio de Castro, Guedes, Paulo Marcos Matta, de Araújo, Aurigena Antunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758650/
https://www.ncbi.nlm.nih.gov/pubmed/26891124
http://dx.doi.org/10.1371/journal.pone.0148868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758650/
https://www.ncbi.nlm.nih.gov/pubmed/26891124
http://dx.doi.org/10.1371/journal.pone.0148868

Ejemplares similares