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Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells

AIM: To evaluate the anti-inflammatory, anti-oxidant and antifibrotic effects of carvedilol (CARV) in rats with ethanol-induced liver injury. METHODS: Liver injury was induced by gavage administration of alcohol (7 g/kg) for 28 consecutive days. Eighty Wistar rats were pretreated with oral CARV at 1...

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Detalles Bibliográficos
Autores principales:	de Araújo Júnior, Raimundo Fernandes, Garcia, Vinícius Barreto, Leitão, Renata Ferreira de Carvalho, Brito, Gerly Anne de Castro, Miguel, Emilio de Castro, Guedes, Paulo Marcos Matta, de Araújo, Aurigena Antunes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758650/ https://www.ncbi.nlm.nih.gov/pubmed/26891124 http://dx.doi.org/10.1371/journal.pone.0148868

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