Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Resistant to Fifth-Generation Cephalosporins Reveals Potential Non-mecA Mechanisms of Resistance

Fifth-generation cephalosporins, ceftobiprole and ceftaroline, are promising drugs for treatment of bacterial infections from methicillin-resistant Staphylococcus aureus (MRSA). These antibiotics are able to bind native PBP2a, the penicillin-binding protein encoded by the mecA resistance determinant...

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Detalles Bibliográficos
Autores principales: Greninger, Alexander L., Chatterjee, Som S., Chan, Liana C., Hamilton, Stephanie M., Chambers, Henry F., Chiu, Charles Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758708/
https://www.ncbi.nlm.nih.gov/pubmed/26890675
http://dx.doi.org/10.1371/journal.pone.0149541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758708/
https://www.ncbi.nlm.nih.gov/pubmed/26890675
http://dx.doi.org/10.1371/journal.pone.0149541

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