Unmasking Heavily O-Glycosylated Serum Proteins Using Perchloric Acid: Identification of Serum Proteoglycan 4 and Protease C1 Inhibitor as Molecular Indicators for Screening of Breast Cancer

Heavily glycosylated mucin glycopeptides such as CA 27.29 and CA 15–3 are currently being used as biomarkers for detection and monitoring of breast cancer. However, they are not well detected at the early stages of the cancer. In the present study, perchloric acid (PCA) was used to enhance detection...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Siang, Taib, Nur Aishah Mohd, Ashrafzadeh, Ali, Fadzli, Farhana, Harun, Faizah, Rahmat, Kartini, Hoong, See Mee, Abdul-Rahman, Puteri Shafinaz, Hashim, Onn Haji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758733/
https://www.ncbi.nlm.nih.gov/pubmed/26890881
http://dx.doi.org/10.1371/journal.pone.0149551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758733/
https://www.ncbi.nlm.nih.gov/pubmed/26890881
http://dx.doi.org/10.1371/journal.pone.0149551

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