Purification and Characterization of Glutaminase Free Asparaginase from Enterobacter cloacae: In-Vitro Evaluation of Cytotoxic Potential against Human Myeloid Leukemia HL-60 Cells

Asparaginase is an important antileukemic agent extensively used worldwide but the intrinsic glutaminase activity of this enzymatic drug is responsible for serious life threatening side effects. Hence, glutaminase free asparaginase is much needed for upgradation of therapeutic index of asparaginase...

Descripción completa

Detalles Bibliográficos
Autores principales: Husain, Islam, Sharma, Anjana, Kumar, Suresh, Malik, Fayaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758734/
https://www.ncbi.nlm.nih.gov/pubmed/26891220
http://dx.doi.org/10.1371/journal.pone.0148877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758734/
https://www.ncbi.nlm.nih.gov/pubmed/26891220
http://dx.doi.org/10.1371/journal.pone.0148877

Ejemplares similares