A Pilot In Vivo Proton Magnetic Resonance Spectroscopy Study of Amino Acid Neurotransmitter Response to Ketamine Treatment of Major Depressive Disorder

The NMDA receptor antagonist ketamine can improve major depressive disorder (MDD) within hours. To evaluate the putative role of glutamatergic and GABAergic systems in ketamine’s antidepressant action, medial prefrontal cortical (mPFC) levels of glutamate + glutamine (Glx) and γ-aminobutyric acid (G...

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Detalles Bibliográficos
Autores principales: Milak, Matthew S., Proper, Caitlin J., Mulhern, Stephanie T., Parter, Amy L., Kegeles, Lawrence S., Ogden, R. Todd, Mao, Xiangling, Rodriguez, Carolyn I., Oquendo, Maria A., Suckow, Raymond F., Cooper, Thomas B., Keilp, John C., Shungu, Dikoma C., Mann, J. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758914/
https://www.ncbi.nlm.nih.gov/pubmed/26283639
http://dx.doi.org/10.1038/mp.2015.83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758914/
https://www.ncbi.nlm.nih.gov/pubmed/26283639
http://dx.doi.org/10.1038/mp.2015.83

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