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Evaluation of polymer shielding for adenovirus serotype 6 (Ad6) for systemic virotherapy against human prostate cancers

Oncolytic viruses hold promise as “self-amplifying” cancer therapies wherein a virally killed cell can produce thousands of new viral “drugs” that can kill more cancer cells. Adenoviruses (Ads) are one family of oncolytic viruses. Most human studies have used human Ad serotype 5 (Ad5). Unfortunately...

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Detalles Bibliográficos
Autores principales: Nguyen, Tien V, Heller, Greg J, Barry, Mary E, Crosby, Catherine M, Turner, Mallory A, Barry, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758940/
https://www.ncbi.nlm.nih.gov/pubmed/26900598
http://dx.doi.org/10.1038/mto.2015.21