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NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
Mitotic spindle orientation is used to generate cell fate diversity and drive proper tissue morphogenesis. A complex of NuMA and dynein/dynactin is required for robust spindle orientation in a number of cell types. Previous research proposed that cortical dynein/dynactin was sufficient to generate f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758947/ https://www.ncbi.nlm.nih.gov/pubmed/26765568 http://dx.doi.org/10.7554/eLife.12504 |