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Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

The size and position of mitotic spindles is determined by the lengths of their constituent microtubules. Regulation of microtubule length requires feedback to set the balance between growth and shrinkage. Whereas negative feedback mechanisms for microtubule length control, based on depolymerizing k...

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Detalles Bibliográficos
Autores principales: Hibbel, Anneke, Bogdanova, Aliona, Mahamdeh, Mohammed, Jannasch, Anita, Storch, Marko, Schäffer, Erik, Liakopoulos, Dimitris, Howard, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758950/
https://www.ncbi.nlm.nih.gov/pubmed/26576948
http://dx.doi.org/10.7554/eLife.10542