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Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe
The size and position of mitotic spindles is determined by the lengths of their constituent microtubules. Regulation of microtubule length requires feedback to set the balance between growth and shrinkage. Whereas negative feedback mechanisms for microtubule length control, based on depolymerizing k...
Autores principales: | Hibbel, Anneke, Bogdanova, Aliona, Mahamdeh, Mohammed, Jannasch, Anita, Storch, Marko, Schäffer, Erik, Liakopoulos, Dimitris, Howard, Jonathon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758950/ https://www.ncbi.nlm.nih.gov/pubmed/26576948 http://dx.doi.org/10.7554/eLife.10542 |
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