Cargando…
Building accurate sequence-to-affinity models from high-throughput in vitro protein-DNA binding data using FeatureREDUCE
Transcription factors are crucial regulators of gene expression. Accurate quantitative definition of their intrinsic DNA binding preferences is critical to understanding their biological function. High-throughput in vitro technology has recently been used to deeply probe the DNA binding specificity...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758951/ https://www.ncbi.nlm.nih.gov/pubmed/26701911 http://dx.doi.org/10.7554/eLife.06397 |