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Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells

Dynamic post-translational modification of RNA polymerase II (RNAPII) coordinates the co-transcriptional recruitment of enzymatic complexes that regulate chromatin states and processing of nascent RNA. Extensive phosphorylation of serine residues at the largest RNAPII subunit occurs at its structura...

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Detalles Bibliográficos
Autores principales: Dias, João D, Rito, Tiago, Torlai Triglia, Elena, Kukalev, Alexander, Ferrai, Carmelo, Chotalia, Mita, Brookes, Emily, Kimura, Hiroshi, Pombo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758952/
https://www.ncbi.nlm.nih.gov/pubmed/26687004
http://dx.doi.org/10.7554/eLife.11215