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Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin

Class III myosins (Myo3) and actin-bundling protein Espin play critical roles in regulating the development and maintenance of stereocilia in vertebrate hair cells, and their defects cause hereditary hearing impairments. Myo3 interacts with Espin1 through its tail homology I motif (THDI), however it...

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Detalles Bibliográficos
Autores principales: Liu, Haiyang, Li, Jianchao, Raval, Manmeet H, Yao, Ningning, Deng, Xiaoying, Lu, Qing, Nie, Si, Feng, Wei, Wan, Jun, Yengo, Christopher M, Liu, Wei, Zhang, Mingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758956/
https://www.ncbi.nlm.nih.gov/pubmed/26785147
http://dx.doi.org/10.7554/eLife.12856