Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex

Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway causes pathology in a family of neurodevelopmental disorders known as 'RASopathies' and is implicated in autism pathogenesis. Here, we have determined the functions of ERK/MAPK signaling in developing neocortical excitatory neur...

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Detalles Bibliográficos
Autores principales: Xing, Lei, Larsen, Rylan S, Bjorklund, George Reed, Li, Xiaoyan, Wu, Yaohong, Philpot, Benjamin D, Snider, William D, Newbern, Jason M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758957/
https://www.ncbi.nlm.nih.gov/pubmed/26848828
http://dx.doi.org/10.7554/eLife.11123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758957/
https://www.ncbi.nlm.nih.gov/pubmed/26848828
http://dx.doi.org/10.7554/eLife.11123

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