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Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex

Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway causes pathology in a family of neurodevelopmental disorders known as 'RASopathies' and is implicated in autism pathogenesis. Here, we have determined the functions of ERK/MAPK signaling in developing neocortical excitatory neur...

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Detalles Bibliográficos
Autores principales:	Xing, Lei, Larsen, Rylan S, Bjorklund, George Reed, Li, Xiaoyan, Wu, Yaohong, Philpot, Benjamin D, Snider, William D, Newbern, Jason M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758957/ https://www.ncbi.nlm.nih.gov/pubmed/26848828 http://dx.doi.org/10.7554/eLife.11123

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