Cargando…

SNP2Structure: A Public and Versatile Resource for Mapping and Three-Dimensional Modeling of Missense SNPs on Human Protein Structures

One of the long-standing challenges in biology is to understand how non-synonymous single nucleotide polymorphisms (nsSNPs) change protein structure and further affect their function. While it is impractical to solve all the mutated protein structures experimentally, it is quite feasible to model th...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Difei, Song, Lei, Singh, Varun, Rao, Shruti, An, Lin, Madhavan, Subha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759123/
https://www.ncbi.nlm.nih.gov/pubmed/26949480
http://dx.doi.org/10.1016/j.csbj.2015.09.002